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Rare Events detection

Unique & sophisticated HCS tools for studying rare events in living cells

  •  Examine your images only when something interesting happens and check the image library to see what exactly had happened
  • Sophisticated detection and readouts techniques for real-time analysis
  • Scanning time is kept to a minimum
  • No additional data mining or image analysis is required to identify cells of interest in high resolution images
  • No wasted data storage of unimportant cells
  • Allows researchers to obtain meaningful data regarding the kinetics of their biological system without investing any extra resources or cost.
  • Hermes uses real-time monitoring so that the relevant signal is never overlooked
  • Hermes achieves better statistical precision than cross-well comparisons of standard end-point imaging studies by applying quantitative, real-time analysis in each of the wells

Performing large scale cell imaging assays?
Ever feel like you’re Looking for a needle in a hay sack?

Visualizing rare events requires systematic, continuous tracking of multi-dimensional aspects of the system, capturing dynamic processes and identifying transient, sometimes unexpected features.
Such tracking must include automatic and highly accurate detection of specific events of interest and the ability to rapidly capture and document those events at high resolution.
WiScan® Hermes incorporates sophisticated HCS tools for studying rare events in living cells.

New: Combined Rare-event Time-Lapse Imaging tool

IDEA Bio recently launched a unique advanced tool for time lapse experiments, which combines the feature of rare event detection (also called object mapping) in defined time intervals, offering a new feature for spatio-temporal analysis of rare events measures, using high-content microscopy.

This is a unique, four-step process for rapid scanning while targeting cells of interest.

  1. The first scan images the entire plate at low magnification (2X-20X), optionally in pre-defined time intervals. This initial scan enables high-speed identification of rare or special cells.
  2.  Automated, on-the-fly image analysis extracts multi-parametric morphological and fluorescence properties for each cell at low
    magnification. Cells having desired rare characteristics, are located and their position is saved.
  3. A precise objective exchanger loads a high magnification 20X-60X objective to re-image all cells identified in Step 2 at high resolution.
  4. All cells identified in step 2 are re-imaged using 20X-60X magnification and/or using z-stack, capturing crisp images full of intracellular detail.









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