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Intranuclear Foci Assay
Automatic detection & quantification of intranuclear foci and puncta
This application detects fluorescent foci within cellular nuclei and quantifies their count, area and intensity.
In parallel, the intensity of a labeled protein of interest in the nuclei is measured and quantified as well.
Single cell analysis of RNA FISH for cytokine expression
In this application note, we utilized WiScan® Hermes high content microscope to investigate immune responses to stimuli by primary human monocyte-derived macrophages, which exhibit significant variability in gene expression between different cells. WiScan® Hermes High content wide field microscope offers the ability to work with large sample sizes while investigating subcellular features at the single cell level.
This application detects fluorescent foci within cellular nuclei and quantifies their count, area and intensity.
In parallel, the intensity of a labeled protein of interest in the nuclei is measured and quantified as well.
Single cell analysis of RNA FISH for cytokine expression
In this application note, we utilized WiScan® Hermes high content microscope to investigate immune responses to stimuli by primary human monocyte-derived macrophages, which exhibit significant variability in gene expression between different cells. WiScan® Hermes High content wide field microscope offers the ability to work with large sample sizes while investigating subcellular features at the single cell level.