Detection of Rare Events in Live Cells
Unique & sophisticated HCS tools for automated tracking & studying rare events in living cells
Performing large scale cell imaging assays?
Ever feel like you’re Looking for a needle in a haystack?
Visualizing rare events requires systematic, continuous tracking of multi-dimensional aspects of the system, capturing dynamic processes and identifying transient, sometimes unexpected features.
Such tracking must include automatic and highly accurate detection of specific events of interest and the ability to rapidly capture and document those events at high resolution.
WiScan® Hermes incorporates sophisticated HCS tools for studying rare events in living cells.
Examine your images only when something interesting happens and check the image library to see what exactly had happened
This unique feature is used for spatial detection and characterization of temporal kinetics of rare events. Using IDEA Bio-Medical’s advanced HCS (high content screening) system, WiScan® Hermes, Based on the microscope’s ultrafast image acquisition properties, the system first scans the entire plate and acquires images using low magnifications (2X-10X) in predefined time intervals. This initial scan automatically spots objects of interest, based on multi-parametric morphological features or fluorescence properties.
This ultrafast scanning capacity is achieved thanks to unique capabilities of the Hermes imaging system,
which include stationary plate (the moving component is the objective) and multi channel simultaneous imaging. A rapid, automatic change of
objectives is activated between scans, followed by a second scan which acquires images and records movies in high magnifications(20X-60X) only for the selected objects of interest(D), which are accurately spotted and captured thanks to rapid focusing and high positioning repeatability of the microscope scanner .
- Sophisticated detection and readouts techniques for real-time analysis
- Scanning time is kept to a minimum
- No additional data mining or image analysis is required to identify cells of interest in high resolution images
- No wasted data storage of unimportant cells
- Allows researchers to obtain meaningful data regarding the kinetics of their biological system without investing any extra resources or cost.
- Hermes uses real-time monitoring so that the relevant signal is never overlooked
- Hermes achieves better statistical precision than cross-well comparisons of standard end-point imaging studies by applying quantitative, real-time analysis in each of the wells
Performing large scale cell imaging assays?
Ever feel like you’re Looking for a needle in a hay sack?
Visualizing rare events requires systematic, continuous tracking of multi-dimensional aspects of the system, capturing dynamic processes and identifying transient, sometimes unexpected features.
Such tracking must include automatic and highly accurate detection of specific events of interest and the ability to rapidly capture and document those events at high resolution.
WiScan® Hermes incorporates sophisticated HCS tools for studying rare events in living cells.
Examine your images only when something interesting happens and check the image library to see what exactly had happened
- Sophisticated detection and readouts techniques for real-time analysis
- Scanning time is kept to a minimum
- No additional data mining or image analysis is required to identify cells of interest in high resolution images
- No wasted data storage of unimportant cells
- Allows researchers to obtain meaningful data regarding the kinetics of their biological system without investing any extra resources or cost.
- Hermes uses real-time monitoring so that the relevant signal is never overlooked
- Hermes achieves better statistical precision than cross-well comparisons of standard end-point imaging studies by applying quantitative, real-time analysis in each of the wells