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Cell Morphology
Measures multiple shape properties of fluorescently labeled cells or objects
- Cell health assays
- Endocytosis
- Phagocytosis
- Cell adherence
- Apoptosis
- Cell Shape Changes
- Sub-cellular features detection & quantifications:
- Nuclei
- Actin Cytoskeleton
- Microtubules
- Golgi
- Vesicles
- Focal adhesions
- Mitochondria
Automated classification of single E. coli cells for high-throughput assays at 60x magnification
Learn how E.coli cell shape indicates cell viability and could potentially be applicable to the identification of novel compounds that induce stationary phase and prevent exponential growth of bacteria. The Hermes® HCS imaging system was applied to acquire time lapse images of E.coli bacteria at 60x magnification. Image analysis was performed with Athena® software using the Cell Morphology application to quantify their populations based on shape.
- Cell health assays
- Endocytosis
- Phagocytosis
- Cell adherence
- Apoptosis
- Cell Shape Changes
- Sub-cellular features detection & quantifications:
- Nuclei
- Actin Cytoskeleton
- Microtubules
- Golgi
- Vesicles
- Focal adhesions
- Mitochondria
Automated classification of single E. coli cells for high-throughput assays at 60x magnification
Learn how E.coli cell shape indicates cell viability and could potentially be applicable to the identification of novel compounds that induce stationary phase and prevent exponential growth of bacteria. The Hermes® HCS imaging system was applied to acquire time lapse images of E.coli bacteria at 60x magnification. Image analysis was performed with Athena® software using the Cell Morphology application to quantify their populations based on shape.
Live Zebrafish imaging at 10x magnification
Video capture from a live Zebrafish larva
With thanks to Dr Gillian Tomlinson from the UCL Division of Infection and Immunity, UCL, UK
Live Zebrafish imaging- Blood flow
Video capture from a live Zebrafish larva imaged in bright field illumination using 40X magnification. Acquired by Dr Gillian Tomlinson using IDEA Bio-Medical’s Hermes WiScan at the UCL Division of Infection and Immunity, London, UK.
Fish organs & regions automatic segmentation
Automatically quantify area, fluorescence intensity, and count of whole fish and internal organelle properties, including eye, yolk, spine, tail, brain, internal granules and more.Statistical data calculated per fish and per organelle.
Time lapse Zebrafish- Neutrophil Migration
Time lapse of a Zebrafish embryo with S. Pneumoniae injected into the hind brain. GFP-expressing Neutrophils begin to migrate into the injection site over 4 hours.Acquired with IDEA Bio-Medical’s Hermes automated screening system by Sreyashi Koyel Basu and Dr. Gillian Tomlinson, UCL, London, UK
Live Zebrafish imaging at 10x magnification
Video capture from a live Zebrafish larva
With thanks to Dr Gillian Tomlinson from the UCL Division of Infection and Immunity, UCL, UK
Live Zebrafish imaging- Blood flow
Video capture from a live Zebrafish larva imaged in bright field illumination using 40X magnification. Acquired by Dr Gillian Tomlinson using IDEA Bio-Medical’s Hermes WiScan at the UCL Division of Infection and Immunity, London, UK.
Fish organs & regions automatic segmentation
Automatically quantify area, fluorescence intensity, and count of whole fish and internal organelle properties, including eye, yolk, spine, tail, brain, internal granules and more.Statistical data calculated per fish and per organelle.
Time lapse Zebrafish- Neutrophil Migration
Time lapse of a Zebrafish embryo with S. Pneumoniae injected into the hind brain. GFP-expressing Neutrophils begin to migrate into the injection site over 4 hours.Acquired with IDEA Bio-Medical’s Hermes automated screening system by Sreyashi Koyel Basu and Dr. Gillian Tomlinson, UCL, London, UK