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Cell Morphology

Measures multiple shape properties of fluorescently labeled cells or objects
  • Cell health assays
  • Endocytosis
  • Phagocytosis
  • Cell adherence
  • Apoptosis
  • Cell Shape Changes
  • Sub-cellular features detection & quantifications:
  • Nuclei
  • Actin Cytoskeleton
  • Microtubules
  • Golgi
  • Vesicles
  • Focal adhesions
  • Mitochondria

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Automated classification of single E. coli cells for high-throughput assays at 60x magnification

Learn how E.coli cell shape indicates cell viability and could potentially be applicable to the identification of novel compounds that induce stationary phase and prevent exponential growth of bacteria. The Hermes® HCS imaging system was applied to acquire time lapse images of E.coli bacteria at 60x magnification. Image analysis was performed with Athena® software using the Cell Morphology application to quantify their populations based on shape.