Hermes and Athena Citations-Cancer research

Citations- Cancer Research

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks.

Kumar, Santosh, et al. ,International Journal of Molecular Sciences 24.10 (2023): 8717. https://doi.org/10.3390/ijms24108717

Novel combination of isovanillin, curcumin, and harmine (GZ17-6.02) enhances cell death and alters signaling in actinic keratoses cells when compared to individual components and two-component combinations

Bordeaux, Zachary A.; Kwatra, Shawn G.; Booth, Laurence; Dent, Paul Anti-Cancer Drugs, Volume 34, Number 4, 18 April 2023, pp. 544-550(7) DOI: https://doi.org/10.1097/CAD.0000000000001425

Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1.

Avinery, L.; Gahramanov, V.; Hesin, A.; Sherman, M.Y. Cancers 2022, 14, 4168. https://doi.org/10.3390/cancers14174168

Cellular responses after (neratinib plus pemetrexed) exposure in NSCLC cells.

Booth, Laurencea; Poklepovic, Andrewb; Hancock, John F.c; Dent, Paula.Anti-Cancer Drugs 34(9):p 1025-1034, October 2023. | DOI: 10.1097/CAD.00000000

Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy

Blokon-Kogan D, Levi-Mann M, Malka-Levy L, et al, Journal for ImmunoTherapy of Cancer 2022;10:e001544. doi: 10.1136/jitc-2020-001544

Effects on mammalian cell transcriptome reveal a plant extract’s medicinal properties: Potential anti-COVID-19 and anti-cancer properties of Sarcopoterium spinosum

M Oz, T Aouizerat, M Salmon-Divon, T Rosenzweig, 2022, Reserach Square, DOI: https://doi.org/10.21203/rs.3.rs-1250188/v1

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A novel, dual action chimera comprising DNA methylating agent and near-IR xanthene-cyanine photosensitizer for combined anticancer therapy

Ebaston Thankarajan, Dipak Walunj, Andrii Bazylevich, Chandrashekhar Prasad, Arkadi Hesin, Leonid Patsenker, Gary Gellerman, Photodiagnosis and Photodynamic Therapy, 2022,102722,ISSN 1572-1000, https://doi.org/10.1016/j.pdpdt.2022.102722.

Targeted methylation facilitates DNA double strand breaks and enhances cancer suppression: A DNA intercalating/methylating dual-action chimera Amonafidazene

Dipak Walunj, Ebaston Thankarajan, Chandrashekhar Prasad, Helena Tuchinsky, Simone Baldan, Michael Y. Sherman, Leonid Patsenker, Gary Gellerman, European Journal of Medicinal Chemistry, Volume 225, 2021, 113811, ISSN 0223-5234, https://doi.org/10.1016/j.ejmech.2021.113811.

Homologous recombination repair creates mutations in non-coding genome that alter Topoisomerase-1 cleavage sites & orchestrates irinotecan resistance

Santosh Kumar, Valid Gahramanov, Julia Yaglom, Shivani Patel, Lukasz Kaczmarczyk, Ivan Alexandrov, Gabi Gerlitz, Mali Salmon-Divon, Michael Y. Sherman, bioRxiv 2021.11.26.470089; doi: https://doi.org/10.1101/2021.11.26.470089

Enhanced signaling via ERBB3/PI3K plays a compensatory survival role in pancreatic tumor cells exposed to [neratinib+ valproate]‏
P Dent, L Booth, A Poklepovic, D Von Hoff, JF Hancock, Cellular Signalling, Jan 2020 00001442

The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells
Jane L. Roberts, Andrew Poklepovic, Laurence Booth, Paul Dent, Cellular Signalling, 2020, 109573, ISSN 0898-6568

Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells
P Dent et al., Oncogene (2019)

Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells
Y Elisha et al., The Royal Society Volume 374, Issue 1779, 01 July 2019

Regorafenib Enhances Lethality of Sildenafil and Curcumin in Colorectal Cancer Cells
KB Owusu, M Director, P Dent , VCU THESES AND DISSERTATIONS, Feb 2019

Palbociclib augments Neratinib killing of tumor cells that is further enhanced by HDAC inhibition
L Booth et al., Cancer Biology &Therapy, 5 September 2018

The CHK1 inhibitor SRA737 synergizes with PARP1 inhibitors to kill carcinoma cells
Laurence Booth, Jane Roberts, Andrew Poklepovic & Paul Dent, Cancer Biology & Therapy, 19 July 2018

Valproate augments Niraparib killing of tumor cells
Laurence Booth et al., Cancer biol ther., June 2018

[Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration.
Booth et al., Oncotarget, 26;9(5):6062-6074, Dec 2017
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Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Evans J. et al., August 2015, eLife 2015;4:e07301. DOI: 10.7554/eLife.07301
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Differential regulation of autophagy and cell viability by ceramide species
Nichola Cruickshanks , Jane L Roberts , M Danielle Bareford , Mehrad Tavallai , Andrew Poklepovic , Laurence Booth , Sarah Spiegel , Paul Dent , Cancer Biology & Therapy Vol. 16, Iss. 5, 2015
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The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib
Laurence Booth t al., Cancer biology & therapy, volume 19, issue 2, 2018
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Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance
Timothy Webb , Jori Carter , Jane L Roberts , Andrew Poklepovic , William P McGuire , Laurence Booth , Paul Dent , Cancer Biology & Therapy Vol. 16, Iss. 11, 2015
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Regulation of OSU-03012 Toxicity by ER Stress Proteins and ER Stress–Inducing Drugs
Booth L. et al.; Mol Cancer Ther, October 2014, 13; 2384
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