IDEA Bio-Medical offers a new feature for spatio-temporal analysis of rare events measures, using high-content microscopy
This new function offers sophisticated HCS tools for studying rare events in living cells. This unique tracking feature includes automatic and
highly accurate detection of specific events of interest, followed by rapid image acquisition and documentation of those events at high resolutions.
Figure : Time lapse rare event steps
This is a three-step process:
A,B: First scan captures the entire plate and acquires
images using low magnification(2X-10X) in pre-defined
time intervals. This initial scan is aimed to spot objects of
interest at very high speed. C: An automatic multiparametric
analysis based on morphological and signal
parameters for object mapping is performed at the end of
each cycle. D: Second scan acquires images and movies in
high magnification(20X-60X) only for objects of interest
selected based on the automated analysis.